Table 4. Association between circulating ANGPTL3 levels and lab values relevant to hepatic impairment or inflammation (n = 800).
A generalized linear model was used. To evaluate AST, ALT or GGT, covariates were adjusted by all variables listed in Table 3, minus the hepatic impairment category. To evaluate hs-CRP, covariates were adjusted by all variables listed in Table 3, minus the inflammation category. β, regression coefficient; 95% CI, 95% confidence interval; AST, aspartate transaminase; ALT, alanine transaminase; GGT, gamma-glutamyltransferase; and hs-CRP, high sensitivity C reactive protein.
log(ANGPTL3) | |||
---|---|---|---|
β | 95%CI | P | |
Hepatic impairment | |||
log(AST) | 0.134 | (0.035, 0.234) | 0.008 |
log(ALT) | 0.035 | (-0.024, 0.095) | 0.243 |
log(GGT) | 0.444 | (0.000, 0.089) | <.050 |
Inflammation | |||
log(hs-CRP) | 0.041 | (0.019, 0.064) | <.001 |