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. 2018 Mar 14;13(3):e0193731. doi: 10.1371/journal.pone.0193731

Table 4. Association between circulating ANGPTL3 levels and lab values relevant to hepatic impairment or inflammation (n = 800).

A generalized linear model was used. To evaluate AST, ALT or GGT, covariates were adjusted by all variables listed in Table 3, minus the hepatic impairment category. To evaluate hs-CRP, covariates were adjusted by all variables listed in Table 3, minus the inflammation category. β, regression coefficient; 95% CI, 95% confidence interval; AST, aspartate transaminase; ALT, alanine transaminase; GGT, gamma-glutamyltransferase; and hs-CRP, high sensitivity C reactive protein.

log(ANGPTL3)
β 95%CI P
Hepatic impairment
    log(AST) 0.134 (0.035, 0.234) 0.008
    log(ALT) 0.035 (-0.024, 0.095) 0.243
    log(GGT) 0.444 (0.000, 0.089) <.050
Inflammation
    log(hs-CRP) 0.041 (0.019, 0.064) <.001