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. Author manuscript; available in PMC: 2019 Feb 13.
Published in final edited form as: Biochemistry. 2018 Jan 24;57(6):991–1002. doi: 10.1021/acs.biochem.7b01172

Figure 3.

Figure 3

Examples of (A) 1H-NMR, (B) CD, and (C) TDS spectra for the BLM and PARP3 PQSs, as well as the (D) Tm and (E) thioflavin-T fluorescence intensities for all PQSs with comparisons to a known G4, dsDNA, and ssDNA controls. Data for all of the sequences are provided in Figure S1. *These sequences failed to provide thermal transitions while monitoring at 295 nm. The 1H-NMR, CD, and Tm data for the NTHL1 PQS were reported in our previous work.13