Figure 3. Microinfarcts in rodent models.

(A) A cortical microinfarct observed in Hematoxylin & Eosin stained mouse brain sections after injection of cholesterol crystals into the internal carotid artery. From Wang et al.¹⁰ (B) A cortical microinfarct observed in NeuN and GFAP immunostained rat brain sections after occlusion of a single cortical penetrating arteriole by focal photothrombosis. From Shih et al.¹² (C) Spontaneous microinfarcts observed in Hematoxylin & Eosin stained brain sections from an 18 months old eNOS-deficient mouse. From Tan et al.¹³ (D) Spontaneous microinfarcts observed in NeuN immunostained brain sections from a 13 months old Townes sickle cell mouse. From Hyacinth et al.¹⁴