Fig. 3.

Mast cells in scar tissue of partial thickness burn wounds at PBD 42.

A toluidine blue staining was performed to indicate the presence of mast cells in scar tissue of partial thickness burn wounds in rats at PBD 42. A) Images of mast cells in scar tissue of the different treatment groups: control, systemic and topical. Tissue sections of the group animals receiving the topical Captopril treatment were divided into two groups: open wounds (down left) and closed wounds (down right). Mast cells are indicated by the purple color and the background is stained light blue. B) Statistical significant higher numbers of mast cells were observed in scar tissue of open wounds which received the topical Captopril treatment compared to closed wounds (p = 0.045; Mann–Whitney U). No statistical significant differences were found between all the different treatments.