Table 1.
Mean, standard deviation and p-value from t-tests for non-coding RNAs in each diagnostic group. Spearman’s rho correlation results for associations with inflammatory cytokines and atypical antipsychotic CPZ equivalents (*p<0.05, **p<0.01). CON: control; SCZ: schizophrenia; AACPZE: atypical antipsychotic CPZ equivalent.
| TMEVPG1 | NRON | HERV-W | HERV-W | ||
|---|---|---|---|---|---|
| M ± SD | M ± SD | M ± SD | M ± SD | ||
| Relative mRNA expression | CON (n=16) SCZ (n=17) p-value |
3.71±1.76 4.95±2.84 .15 |
2.21±0.95 2.59±0.92 .25 |
1.78±0.43 env 2.08±0.67 .15 |
1.88±0.42 gag 2.27±0.74 .09 |
| rs, p | rs, p | rs, p | rs, p | ||
| IL-6 | All (n=33) CON (n=16) SCZ (n=17) |
.56, .001** .30, .26 .66, .007** |
.67, .000** .69, .003** .63, .007** |
.47, .006** .68, .006** .39, .12 |
.49, .005** .17, .55 .63, .009** |
| TNF-α | All (n=33) CON (n=16) SCZ (n=17) |
−.01, .96 −.14, .61 −.17, .52 |
.03, .85 −.34, .19 .14, .61 |
.01, .98 −.14, .63 −.06, .83 |
.00, .99 −.34, .22 .04, .89 |
| IFN-γ | All (n=33) CON (n=16) SCZ (n=17) |
.22, .25 .45, .11 .31, .24 |
.29, .11 .36, .21 .33, .20 |
.17, .39 .13, .68 .34, .18 |
.38, .04* .80, .001** .36, .18 |
| AACPZE (n=12) | −.46, .13 | −.42, .17 | −.65, .02* | −.70, .01* | |