Table 1. Characteristics of sepsis inpatients stratified by site and pre-sepsis healthcare encounters.
Healthcare encounters represent clinician-based encounters (i.e., excluding laboratory, pharmacy, or radiology visits). Values are presented as median (interquartile range) or number (%). VA: Veterans Health Administration; KPNC: Kaiser Permanente Northern California. Sepsis hospitalizations from KPNC include only those originating in the emergency department while those from VA included those originating from any source.
| KPNC | VA | |||||
|---|---|---|---|---|---|---|
| Characteristic | Pre-Sepsis Healthcare Visits | Pre-Sepsis Healthcare Visits | ||||
| No | Yes | p-value | No | Yes | p-value | |
| Number | 6,911 (47.1%) | 7,747 (52.9%) | 17,089 (54.5%) | 14,280(45.5%) | ||
| Age, years | 75 (62–84) | 74 (62–83) | <0.01 | 68 (60–80) | 69 (61–80) | <0.01 |
| Male gender | 3,392 (49.1) | 3,849 (49.7) | 0.94 | 16,572 (97.0) | 13,846 (97.0) | 0.95 |
| Charlson Index | 1 (1 – 2) | 2 (1 – 3) | <0.01 | 3 (1–5) | 3 (1–5) | <0.01 |
| Length of stay, days | 5 (3 – 8) | 5 (3 – 9) | <0.01 | 7 (4–14) | 7 (4–14) | 0.57 |
| Emergency admission | 6,911 (100.0) | 7,747 (100.0) | -- | 9,619 (56.3) | 6,988 (48.9) | <0.01 |
| Intensive care utilization | 3,272 (47.3) | 3,838 (49.5) | 0.10 | 7,143 (41.8) | 5,638 (39.5) | <0.01 |
| Discharge disposition | ||||||
| Death | 953 (13.8) | 1,374 (17.7) | <0.01 | 2,219 (13.0) | 1,974 (13.8) | 0.03 |
| Home | 4,354 (63.0) | 4,223 (54.5) | <0.01 | 14,870 (87.0) | 12,306 (86.2) | 0.03 |