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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Cerebellum. 2018 Apr;17(2):165–172. doi: 10.1007/s12311-017-0891-4

Table 1.

Demographic and Clinical Comparison of ET Cases and Controls

Variable ET Cases Controls Significance
N 45 35
Age in years 74.98 ± 6.16 73.26 ± 6.06 0.22a
Male gender 26 (57.8) 10 (28.6) 0.009b
Right handed 38 (84.4) 31 (88.6) 0.85c
White race 43 (95.6) 32 (91.4) 0.65c
Married 28 (62.2) 22 (62.9) 0.95b
Education (years) 17.9 ± 3.7 [18.0] 18.2 ± 4.8 [17.5] 0.87d
Current smoker 1 (2.2) 1 (2.9) 1.00c
MoCA score 27.5 ± 2.3 [28.0] 28.2 ± 1.7 [28.0] 0.22d
Number of prescription medications 3.5 ± 2.5 [3.0] 3.2 ± 2.9 [3.0] 0.40d
Ethanol use
 <1 drink/week
 <1 drink/day
 1 drink/day
 > 1 drink/day

21 (46.7)
14 (31.1)
3 (6.7)
7 (15.6)

20 (57.1)
6 (17.1)
5 (14.3)
4 (11.4)
0.34b
Total tremor score 21.5 ± 4.1 [22.0] 5.6 ± 2.3 [5.0] <0.001d
Neck or jaw tremor 26 (57.8) NA NA
Age of tremor onset in years 41.5 ± 20.4 [47.5] NA NA
Tremor duration in years 34.0 ± 19.6 [30.0] NA NA
Prescribed medication for tremor at some point 29 (64.4) NA NA
Left dentate volume (c.c.) 1.37 ± 0.22 1.40 ± 0.21 0.42a
Right dentate volume (c.c.) 1.47 ± 0.24 1.49 ± 0.21 0.69a
Left dentate GABA concentration (i.u.) 1.68 ± 0.49 1.80 ± 0.53 0.69a
Right dentate GABA concentration (i.u.) 2.01 ± 0.45 1.86 ± 0.53 0.53a

All values represent mean ± standard deviation or number (percentage).

c.c. = cubic centimeters, i.u. = institutional units, MoCA = Montreal Cognitive Assessment.

a

Student’s t test

b

Chi-square test

c

Fisher’s exact test

d

Mann-Whitney test