Table 1.
Cellular mechanisms that are potentially applicable for genetic engineering of GP migration.
| Mechanism | Molecule/medium | Cell type | Reference |
|---|---|---|---|
| Attraction | CD44 | Astrocyte precursor | Bourguignon et al., 2007 |
| CXCL16/CXCR4 axis | CXCR6-positive GP | Hattermann et al. 2008 | |
| PDGF | Oligodendrocyte precursor | Armstrong et al., 1990 | |
| SDF-1-CXC-4 | Hematopoetic stem cell | Janowski. 2009 | |
| MSC | Nowakowski et al., 2016 | ||
| EPC | Li et al., 2012 | ||
| HGF-c-Met | Tumor cell | Wallace et al., 2013 | |
| IGF-1 | Cardiac stem cell | O’Neill ey al., 2016 | |
| Vascular smooth muscle cell | Beneit et al., 2016 | ||
| Repulsion | CSPGs | GP | Yuan et al., 2016 |
| Nestrin 1 | Small NG2-positive GP | Sugimoto et al., 2001 | |
| Sema3a | Large NG2-positive GP | Sugimoto et al., 2001 | |
| Glioma cell line | Nasarre et al., 2009 | ||
| TGFβ1 | OPC | Choe et al., 2009 | |
| EGF | Newborn glia | Kuhn et al., 2009 | |
| Motility regulation | AQP4 | Astroglia | Ding et al, 2011 |
| NCAM | GP | Wang et al. 1994 | |
| Sox5 and Sox6 | Oligodendroglial cell | Baroti et al., 2016 | |
| ZEB-1 | Epithelial cancer cell | Zhang et al., 2015 | |
| NSC | Kahlert et al., 2015 | ||
| Electric field | Schwann cells, MSCs, and pluripotent stem cells | Iwasa et al. 2017 | |
| OPC | Zhu et al. 2016 |