Figure 1.
Gene expression and serum levels of CXCL10 in C57BL/6 and MRL/MpJ mice following fracture. (A) RT-PCR data showing relative change of CXCL10 gene expression in synovial tissue from C57BL/6 mice (black bars) and MRL/MpJ mice (light bars) (n=6 for each strain) following fracture (fx). Top shows fold change from Pre-Fracture (Pre-Fx) for each strain and bottom shows fold change in MRL/MpJ (MRL) strain compared to C57BL/6 (B6) strain. Greater than 3-fold change in expression was considered significant. (B) Serum concentrations of CXCL10 from C57BL/6 (black bars) and MRL/MpJ (light bars) mice following fracture (fx), data presented as mean ± SEM (Mann-U Whitney, *p < 0.05).