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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: J Orthop Res. 2017 Nov 20;36(4):1220–1227. doi: 10.1002/jor.23735

Figure 3.

Figure 3

Effect of exogenous CXCL10 on cartilage explants. All outcomes measured in media from cartilage explants cultured in different concentrations of CXCL10 (0, 1, 10, 100 ng/ml). Data normalized to wet weight of cartilage and reported as mean ± SEM with statistical analysis using one-way ANOVA with trend analysis. (A) MMP activity in fluorescent units/mg of cartilage (r = −0.55, p = 0.006). (B) Aggrecanase-1 (ADAMTS-4) activity in fluorescent units/ mg of cartilage (r = −0.40, p = 0.05). (C) S-GAG release in μg/mg of cartilage (r = −0.30, p = 0.15). (D) NO release in μM/mg of cartilage (r = −0.25, p = 0.22).