Table 3.
UA vascular parameters in NP, P14 and P18 BKCa −/− and γ1−/− mice
| BKCa −/− dams | γ1−/− dams | |||||
|---|---|---|---|---|---|---|
| NP (8) | P14 (9) | P18 (13) | NP (4) | P14 (5) | P18 (6) | |
| Wall thickness (μm) | 30.8 ± 1.8 | 38 ± 2.2 | 38.7 ± 1.9 | 30 ± 2.6 | 36.2 ± 1.2 | 41.5 ± 3.1 |
| Cross‐sectional area (103 μm2) | 28.8 ± 2.2 | 62.2 ± 5.2† | 57.7 ± 3.9† | 28.8 ± 2.7 | 53.6 ± 2.8 | 57.6 ± 5.6† |
| Wall:lumen ratio | 11.8 ± 1.1 | 8.5 ± 0.5 | 9.2 ± 0.8 | 11 ± 1.2 | 8.3 ± 0.2 | 10.6 ± 1.1 |
Data are means ± SEM and number of vessels are in parentheses. † P < 0.05 compared to NP of same genotype. 2‐way ANOVA, Sidak.