Table 2.
Overview of REEG studies on alcohol addiction
| Methods | Findings | |
|---|---|---|
| Features | Participants | |
| Spectral power | 191 detoxified patients and 240 controls (Coutin-Churchman et al. 2006) | Significant correlation between decreased power of slow bands and cortical atrophy in detoxified patients |
| Increased power in beta band correlated with medication, clinical seizures and family history of AUD | ||
| 22 detoxified patients and 58 controls (Saletu-Zyhlarz et al. 2004) | Decrease delta and slow alpha power, increase beta power in alcoholics compared with controls | |
| 6 months abstainers showed an increase of slow band and fast beta, a decrease in fast alpha and slow beta | ||
| 307 alcoholics and 307 controls (Rangaswamy et al. 2002, 2003) | Increased theta power at all scalp locations, prominent at the central and parietal in male, and at the parietal in female in alcoholics as compared with controls | |
| Increased low beta (12–20 Hz) power in the whole brain, but most prominent in the central and parietal, increased high beta (20–30 Hz) power in frontal | ||
| The increase of beta power was more prominent in male alcoholics than female | ||
| People with family history of AD including 108 Hispanic and 269 non-Hispanic (Ehlers et al. 2004) | Low voltage alpha in alcoholics | |
| Alpha amplitude may be associated with ethnic variation, but not drinking status, family history of AD, or other disorders | ||
| Female with family history of AD were found to have higher slow alpha (8–9 Hz) and beta power than male | ||
| 61 alcoholics and 176 controls (Ehlers and Phillips 2007) | AD was associated with LVA in occipital areas and in men only | |
| No association between alpha amplitude and family history of AD | ||
| 48 relapsers, 59 abstainers and 22 controls (Bauer 2001) | Achieve accuracy with 61% sensitivity, 85% specificity, 75% positive predictive and 74% negative predictive respectively using logistic regression | |
| Coherence and phase delay | 77 alcoholics and 45 controls (Tcheslavski and Gonen 2012) | Spectral power and coherence of slow bands in alcoholics are lower than in controls |
| Phase synchrony of alcoholics also reduced in α2 (10–12 Hz) and β1 (12–20 Hz) frequency at central region | ||
| Synchronization likelihood (SL) | 11 heavy drinkers and 11 light drinkers (de Bruin et al. 2004) | The increases in theta and gamma synchronization that of heavy drinkers might indicate damages in hippocampal–neocortical connectivity |
| 18 light, 33 moderate and 34 heavy drinkers (de Bruin et al. 2006) | Low synchronization of alpha and slow-beta in left hemisphere in heavy drinkers | |
| Lower synchronization of fast-beta band in moderate and heavy male drinkers | ||