. 2018 Mar 14;8:4482. doi: 10.1038/s41598-018-22767-y

Table 1.

Summary of 12 miRNAs selected as candidates for novel tumor suppressive miRNAs in functional based screening with Pre-miR miRNA Precursor Library v15.

miRNA Precursor	Mature Sequence	Panc1 #1	Panc1 #2	Location	Host gene	Annotation Confidence (miRBase)	Ref^‡
miRNA Precursor	Mature Sequence	Ratio^†	Ratio^†	Location	Host gene	Annotation Confidence (miRBase)	Ref^‡
hsa-miR-342-5p	AGGGGUGCUAUCUGUGAUUGA	0.432	0.323	14q32.2	EVL	high	³⁵
has-miR-449b*	CAGCCACAACUACCCUGCCACU	0.357	0.446	5q11.2	CDC20		—
hsa-miR-608	AGGGGUGGUGUUGGGACAGCUCCGU	0.487	0.503	10q24.31	SEMA4G		³⁵
hsa-miR-634	AACCAGCACCCCAACUUUGGAC	0.443	0.579	17q24.2	PRKCA		³⁶
hsa-miR-671-3p	UCCGGUUCUCAGGGCUCCACC	0.563	0.467	7q36.1	CHPF2	high	³⁷
hsa-miR-876-3p	UGGUGGUUUACAAAGUAAUUCA	0.407	0.439	9p21.1	LINGO2	high	³⁸
hsa-miR-1289	UGGAGUCCAGGAAUCUGCAUUUU	0.576	0.338	20q11.22	GDF5		—
hsa-miR-1289	UGGAGUCCAGGAAUCUGCAUUUU	0.576	0.338	5q31.1	FSTL4
hsa-miR-1293	UGGGUGGUCUGGAGAUUUGUGC	0.580	0.425	12q13.12	LIMA1		—
hsa-miR-3126-3p	CAUCUGGCAUCCGUCACACAGA	0.582	0.533	2p13.3	ANTXR1		—
hsa-miR-3140	AGCUUUUGGGAAUUCAGGUAGU	0.508	0.459	4q31.3	FBXW7	high	—
hsa-miR-3165	AGGUGGAUGCAAUGUGACCUCA	0.533	0.370	11q13.4	NUMA1		—
hsa-miR-3173		0.551	0.372	14q32.13	DICER1		—

^†Ratio means the cell growth ratio of viable cells as assessed by crystal violet staining 72 hours after transfection with miRNAs, relative to the control transfectants. ^‡Reference is TS-miRNA.