Table 1.
Analyses of the gene usage from the heavy-chain complementarity-determining region 3 (HCDR3)-specific non-selected population.
| Clone ID | VH gene | DH gene | JH gene | HCDR3 | VL gene | JL gene | LCDR3 |
|---|---|---|---|---|---|---|---|
| C7 | IGHV1-2 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV2-28 | IGKJ3 | CMQTLQTPFTF |
| G12 | IGHV1-2 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGLV2-14 | IGLJ1 | CSSYTSVSTYVF |
| E2 | IGHV1-2 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGLV7-46 | IGLJ2 | CLLDYTDARVF |
| D7 | IGHV1-3 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV1-39 | IGKJ1 | CQQSYSTPWTF |
| A6 | IGHV1-46 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV2-28 | IGKJ4 | CMQSLQTPLTF |
| C9 | IGHV1-46 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGLV2-8 | IGLJ2 | CSSYAGSNNVVF |
| D2 | IGHV1-46 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGLV2-14 | IGLJ1 | CCSYGGPYVF |
| H11 | IGHV1-46 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV1-5 | IGKJ4 | CQQYYSTPLTF |
| A12 | IGHV1-69 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGLV1-40 | IGLJ1 | CQSYDSSLSGYVF |
| H10 | IGHV1-69 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGLV2-18 | IGLJ1 | CSSYTSSSTYVF |
| B2 | IGHV3-21 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV1-12 | IGKJ3 | CQQTNSFPFTF |
| D9 | IGHV3-21 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV1-9 | IGKJ5 | CHQTDTLPITF |
| A11 | IGHV3-23 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV1-5 | IGKJ2 | CQQYDTLPRTF |
| B5 | IGHV3-23 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV1-39 | IGKJ4 | CQQSYSTPPTF |
| G4 | IGHV3-23 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV4-1 | IGKJ2 | CQQYHSTPYTF |
| A2 | IGHV3-23 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV1-5 | IGKJ2 | CQQYVECSF |
| A5 | IGHV3-23 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV2-28 | IGKJ2 | CMQALQSPRTF |
| A8 | IGHV3-23 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV3-11 | IGKJ2 | CQQYNNWPPYTF |
| B4 | IGHV3-23 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV1-17 | IGKJ4 | CLQHNLYPRTF |
| D1 | IGHV3-23 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV3D-15 | IGKJ4 | CQQYNNWPPLTF |
| D4 | IGHV3-23 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV3D-20 | IGKJ2 | CQQFGGSPKCSF |
| E1 | IGHV3-23 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV1-17 | IGKJ4 | CLQHNTYPLTF |
| F2 | IGHV3-23 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV2-28 | IGKJ1 | CMQALQTPWTF |
| G2 | IGHV3-23 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGLV3-1 | IGLJ2 | CQVWDSNSHVVF |
| G5 | IGHV3-23 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV3D-20 | IGKJ5 | CQQRSNWPLTF |
| B3 | IGHV3-23 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGLV2-14 | IGLJ2 | CAAWDSSLSAVVF |
| A1 | IGHV3-30 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV1-33 | IGKJ5 | CQQYDKLPLTF |
| B1 | IGHV3-30 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV1-12 | IGKJ2 | CQQGYSFPRTF |
| D12 | IGHV3-53 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGLV3-21 | IGLJ2 | CQAWDTHDDPWGVF |
| E5 | IGHV3-64 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV1-33 | IGKJ2 | CVQHRGYPRYTF |
| C10 | IGHV3-64D | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV3-11 | IGKJ3 | CQQRINRVTF |
| A3 | IGHV3-7 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV3D-20 | IGKJ3 | CQQYSLYPLSF |
| G9 | IGHV3-7 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGLV1-44 | IGLJ1 | CQAWDSRTAVF |
| B8 | IGHV3-72 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV1-9 | IGKJ4 | CQQLNSYPLAF |
| G3 | IGHV3-9 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV3-11 | IGKJ5 | CQQRGNWPPGATF |
| G1 | IGHV4-31 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGLV3-1 | IGLJ2 | CQAWDSGTVVF |
| B6 | IGHV4-31 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV2-28 | IGKJ2 | CMQALQSPRTF |
| H1 | IGHV4-31 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGLV3-1 | IGLJ2 | CQAWDSSTAVF |
| F1 | IGHV4-34 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV1-17 | IGKJ1 | CLQHNNYPRTF |
| G8 | IGHV4-34 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV2D-29 | IGKJ2 | CMQGTHWPRTF |
| H5 | IGHV4-34 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV4-1 | IGKJ4 | CQQYYSTPLTF |
| A10 | IGHV4-34 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV1-17 | IGKJ1 | CLQHNNYPRTF |
| E3 | IGHV4-34 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV2-28 | IGKJ1 | CMQALQAPWTL |
| F4 | IGHV4-34 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGLV3-21 | IGLJ2 | CQVWDSRDQHVAF |
| A7 | IGHV4-34 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV1-33 | IGKJ2 | CQQYDNLRYSF |
| E12 | IGHV4-34 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV3-11 | IGKJ2 | CQQRSNSPPFTF |
| C4 | IGHV4-4 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGLV1-51 | IGLJ3 | CGTWDSSLSAGVF |
| B7 | IGHV4-59 | IGHD3-10 | IGHJ3 | CAKGFRAGDAFDIW | IGKV4-1 | IGKJ3 | CQQFYSTPPLFTF |
| C8 | IGHV4-61 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGLV2-8 | IGLJ2 | CSSYTGSNNWRVVF |
| A9 | IGHV5-51 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV1-5 | IGKJ3 | CQQSYSTPLFTF |
| C6 | IGHV5-51 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV1-5 | IGKJ4 | CLQHDEYPLTF |
| E6 | IGHV5-51 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV1-5 | IGKJ4 | CQQADSVPLTF |
| F7 | IGHV5-51 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV4-1 | IGKJ3 | CQQYSSIPFTF |
| F8 | IGHV5-51 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGLV7-43 | IGLJ3 | CLLYYGGAQLGVF |
| G11 | IGHV5-51 | IGHD2-8 | IGHJ3 | CAKGFRAGDAFDIW | IGKV1-39 | IGKJ1 | SQQSYDSPPMTF |