Table 2.
Analyses of (A) DeKosky and (B) DeWitt data for identical HCDR3s.
| (A) | ||||||
| HCDR3 aa sequence | Length | VH family | VH gene | DH gene | JH gene | |
| CAKDGYW | 5 | IGHV01 | IGHV1-46 | IGHJ4 | ||
| CAKDGYW | 5 | IGHV03 | IGHV3-23 | IGHJ4 | ||
| CARADDAFDIW | 9 | IGHV01 | IGHV1-69 | IGHJ3 | ||
| CARADDAFDIW | 9 | IGHV04 | IGHV4-34 | IGHD1-1 | IGHJ3 | |
| CARALYYFDYW | 9 | IGHV01 | IGHV1-46 | IGHD1-7 | IGHJ4 | |
| CARALYYFDYW | 9 | IGHV01 | IGHV1-2 | IGHD3-16 | IGHJ4 | |
| CARDKYYFDYW | 9 | IGHV01 | IGHV1-69 | IGHD1-14 | IGHJ4 | |
| CARDKYYFDYW | 9 | IGHV04 | IGHV4-59 | IGHJ4 | ||
| CARDLDYW | 6 | IGHV03 | IGHV3-11 | IGHJ4 | ||
| CARDLDYW | 6 | IGHV03 | IGHV3-33 | IGHJ4 | ||
| CARDPFDYW | 7 | IGHV01 | IGHV1-69 | IGHJ4 | ||
| CARDPFDYW | 7 | IGHV01 | IGHV1-46 | IGHJ4 | ||
| CARDPGPW | 6 | IGHV01 | IGHV1-69 | IGHD1-14 | IGHJ5 | |
| CARDPGPW | 6 | IGHV03 | IGHV3-33 | IGHD1-14 | IGHJ5 | |
| CARDRSSSFDYW | 10 | IGHV03 | IGHV3-33 | IGHD6-13 | IGHJ4 | |
| CARDRSSSFDYW | 10 | IGHV03 | IGHV3-74 | IGHD6-13 | IGHJ4 | |
| CARDSGNDYW | 8 | IGHV07 | IGHV7-4 | IGHD6-13 | IGHJ4 | |
| CARDSGNDYW | 8 | IGHV01 | IGHV1-8 | IGHD4-23 | IGHJ4 | |
| CARDSSGYFDYW | 10 | IGHV01 | IGHV1-46 | IGHD3-22 | IGHJ4 | |
| CARDSSGYFDYW | 10 | IGHV01 | IGHV1-18 | IGHD3-22 | IGHJ4 | |
| CARDYCSGGSCYFDYW | 14 | IGHV04 | IGHV4-31 | IGHD2-15 | IGHJ4 | |
| CARDYCSGGSCYFDYW | 14 | IGHV03 | IGHV3-21 | IGHD2-15 | IGHJ4 | |
| CARGAAPDYW | 8 | IGHV01 | IGHV1-46 | IGHD5-12 | IGHJ4 | |
| CARGAAPDYW | 8 | IGHV03 | IGHV3-53 | IGHD2-15 | IGHJ4 | |
| CARGAYYFDYW | 9 | IGHV04 | IGHV4-59 | IGHD3-16 | IGHJ4 | |
| CARGAYYFDYW | 9 | IGHV03 | IGHV3-33 | IGHJ4 | ||
| CARGGNWFDPW | 9 | IGHV04 | IGHV4-34 | IGHD3-10 | IGHJ5 | |
| CARGGNWFDPW | 9 | IGHV04 | IGHV4-30 | IGHD2-15 | IGHJ5 | |
| CARGGYGDYVDYW | 11 | IGHV01 | IGHV1-46 | IGHD4-17 | IGHJ4 | |
| CARGGYGDYVDYW | 11 | IGHV01 | IGHV1-18 | IGHD4-17 | IGHJ4 | |
| CARGIAAADYW | 9 | IGHV03 | IGHV3-48 | IGHD6-13 | IGHJ4 | |
| CARGIAAADYW | 9 | IGHV01 | IGHV1-69 | IGHD6-13 | IGHJ4 | |
| CARGRVFDYW | 8 | IGHV04 | IGHV4-34 | IGHD3-16 | IGHJ4 | |
| CARGRVFDYW | 8 | IGHV02 | IGHV2-5 | IGHD1-26 | IGHJ4 | |
| CARGSSFDYW | 8 | IGHV04 | IGHV4-59 | IGHD3-10 | IGHJ4 | |
| CARGSSFDYW | 8 | IGHV03 | IGHV3-53 | IGHD6-6 | IGHJ4 | |
| CARGVAARDYW | 9 | IGHV04 | IGHV4-59 | IGHD6-6 | IGHJ4 | |
| CARGVAARDYW | 9 | IGHV03 | IGHV3-48 | IGHD6-6 | IGHJ4 | |
| CARRFDPW | 6 | IGHV03 | IGHV3-21 | IGHJ5 | ||
| CARRFDPW | 6 | IGHV04 | IGHV4-34 | IGHJ5 | ||
| CARRLGNWYFDLW | 11 | IGHV03 | IGHV3-11 | IGHD3-10 | IGHJ2 | |
| CARRLGNWYFDLW | 11 | IGHV04 | IGHV4-61 | IGHD7-27 | IGHJ2 | |
| CARVGSGWYFDYW | 11 | IGHV03 | IGHV3-66 | IGHD6-19 | IGHJ4 | |
| CARVGSGWYFDYW | 11 | IGHV03 | IGHV3-7 | IGHD6-19 | IGHJ4 | |
| CASNDAFDIW | 8 | IGHV01 | IGHV1-46 | IGHJ3 | ||
| CASNDAFDIW | 8 | IGHV05 | IGHV5-10 | IGHJ3 | ||
| (B) | ||||||
| HCDR3 aa Sequence | # rearrangements | VH family | VH gene | DH gene | JH gene | Donor representation |
| CARDRGDYW | 26 | IGHV01 | IGHV01-02 | IGHD03-10 | IGHJ04-01 | donor1 |
| CARDRGDYW | 26 | IGHV01 | IGHV01-02 | IGHD05-24 | IGHJ04-01 | donor3 |
| CARDRGDYW | 26 | IGHV01 | IGHV01-03 | IGHD01-26 | IGHJ04-01 | donor3 |
| CARDRGDYW | 26 | IGHV01 | IGHV01-03 | IGHD03-10 | IGHJ04-01 | donor3 |
| CARDRGDYW | 26 | IGHV01 | IGHV01-03 | IGHD06-25 | IGHJ04-01 | donor1 |
| CARDRGDYW | 26 | IGHV01 | IGHV01-18 | IGHD03-10 | IGHJ04-01 | donor3 |
| CARDRGDYW | 26 | IGHV01 | IGHV01-18 | IGHD03-16 | IGHJ04-01 | donor1, donor3 |
| CARDRGDYW | 26 | IGHV01 | IGHV01-18 | IGHD05-24 | IGHJ04-01 | donor2 |
| CARDRGDYW | 26 | IGHV01 | IGHV01-18 | IGHD06-25 | IGHJ04-01 | donor3 |
| CARDRGDYW | 26 | IGHV01 | IGHV01-46 | IGHD03-10 | IGHJ04-01 | donor1, donor2, donor3 |
| CARDRGDYW | 26 | IGHV01 | IGHV01-46 | IGHD03-16 | IGHJ04-01 | donor2 |
| CARDRGDYW | 26 | IGHV01 | IGHV01-69 | IGHD03-10 | IGHJ04-01 | donor1, donor2, donor3 |
| CARDRGDYW | 26 | IGHV01 | IGHV01-69 | IGHD03-16 | IGHJ04-01 | donor2 |
| CARDRGDYW | 26 | IGHV03 | IGHV03-11 | IGHD03-10 | IGHJ04-01 | donor1 |
| CARDRGDYW | 26 | IGHV03 | IGHV03-11 | IGHD03-16 | IGHJ04-01 | donor1 |
| CARDRGDYW | 26 | IGHV03 | IGHV03-13 | IGHD03-10 | IGHJ04-01 | donor1 |
| CARDRGDYW | 26 | IGHV03 | IGHV03-48 | IGHD03-10 | IGHJ04-01 | donor3 |
| CARDRGDYW | 26 | IGHV03 | IGHV03-53 | IGHD03-10 | IGHJ04-01 | donor1, donor3 |
| CARDRGDYW | 26 | IGHV03 | IGHV03-53 | IGHD03-16 | IGHJ04-01 | donor3 |
| CARDRGDYW | 26 | IGHV03 | IGHV03-53 | IGHD05-24 | IGHJ04-01 | donor1 |
| CARDRGDYW | 26 | IGHV03 | IGHV03-64 | IGHD03-10 | IGHJ04-01 | donor1, donor3 |
| CARDRGDYW | 26 | IGHV03 | IGHV03-66 | IGHD03-10 | IGHJ04-01 | donor2, donor3 |
| CARDRGDYW | 26 | IGHV04 | IGHV04-39 | IGHD03-10 | IGHJ04-01 | donor1, donor3 |
| CARDRGDYW | 26 | IGHV04 | IGHV04-39 | IGHD03-16 | IGHJ04-01 | donor3 |
| CARDRGDYW | 26 | IGHV05 | IGHV05-51 | IGHD03-16 | IGHJ04-01 | donor2 |
| CARDRGDYW | 26 | IGHV07 | IGHV07-04 | IGHD03-10 | IGHJ04-01 | donor3 |
| CARDSSGWYYFDYW | 20 | IGHV01 | IGHV01-02 | IGHD06-19 | IGHJ04-01 | donor1, donor2, donor3 |
| CARDSSGWYYFDYW | 20 | IGHV01 | IGHV01-03 | IGHD06-19 | IGHJ04-01 | donor1, donor2, donor3 |
| CARDSSGWYYFDYW | 20 | IGHV01 | IGHV01-08 | IGHD06-19 | IGHJ04-01 | donor1 |
| CARDSSGWYYFDYW | 20 | IGHV01 | IGHV01-18 | IGHD06-19 | IGHJ04-01 | donor1, donor2, donor3 |
| CARDSSGWYYFDYW | 20 | IGHV01 | IGHV01-46 | IGHD06-19 | IGHJ04-01 | donor1, donor3 |
| CARDSSGWYYFDYW | 20 | IGHV01 | IGHV01-69 | IGHD06-19 | IGHJ04-01 | donor2, donor3 |
| CARDSSGWYYFDYW | 20 | IGHV02 | IGHV02-70 | IGHD06-19 | IGHJ04-01 | donor1, donor3 |
| CARDSSGWYYFDYW | 20 | IGHV03 | IGHV03-11 | IGHD06-19 | IGHJ04-01 | donor1 |
| CARDSSGWYYFDYW | 20 | IGHV03 | IGHV03-20 | IGHD06-19 | IGHJ04-01 | donor1 |
| CARDSSGWYYFDYW | 20 | IGHV03 | IGHV03-23 | IGHD06-19 | IGHJ04-01 | donor3 |
| CARDSSGWYYFDYW | 20 | IGHV03 | IGHV03-48 | IGHD06-19 | IGHJ04-01 | donor3 |
| CARDSSGWYYFDYW | 20 | IGHV03 | IGHV03-53 | IGHD06-19 | IGHJ04-01 | donor1, donor2, donor3 |
| CARDSSGWYYFDYW | 20 | IGHV03 | IGHV03-64 | IGHD06-19 | IGHJ04-01 | donor3 |
| CARDSSGWYYFDYW | 20 | IGHV03 | IGHV03-66 | IGHD06-19 | IGHJ04-01 | donor2, donor3 |
| CARDSSGWYYFDYW | 20 | IGHV03 | IGHV03-72 | IGHD06-19 | IGHJ04-01 | donor3 |
| CARDSSGWYYFDYW | 20 | IGHV03 | IGHV03-74 | IGHD06-19 | IGHJ04-01 | donor1, donor2 |
| CARDSSGWYYFDYW | 20 | IGHV04 | IGHV04-39 | IGHD06-19 | IGHJ04-01 | donor3 |
| CARDSSGWYYFDYW | 20 | IGHV05 | IGHV05-51 | IGHD06-19 | IGHJ04-01 | donor3 |
| CARDSSGWYYFDYW | 20 | IGHV06 | IGHV06-01 | IGHD06-19 | IGHJ04-01 | donor1, donor2 |
| CARDSSGWYYFDYW | 20 | IGHV07 | IGHV07-04 | IGHD06-19 | IGHJ04-01 | donor3 |