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. 2018 Mar 8;9:133. doi: 10.3389/fneur.2018.00133

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Copyright © 2018 Tanaka, Ogawa, Mukai, Sato, Hamazaki, Nagamura-Inoue, Harada-Shiba, Shintaku and Tsuji.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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In vivo imaging of intravenously injected umbilical cord-derived MSCs (UC-MSCs). (A) Representative images of in vivo imaging taken at 3 h, 24 h, and 48 h and 4 days and 7 days after the intravenous injection of UC-MSCs. (B) Quantification of the total photon flux in the vehicle- and UC-MSC-treated groups. UC-MSCs were trapped in the lungs, and the intensity of photon flux decreased over time. We did not detect the signal in brain tissue (vehicle n = 1 and UC-MSC n = 7).