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. 2018 Mar 14;8:4520. doi: 10.1038/s41598-018-22129-8

Table 2.

Promoter predictions in six systems using “PromPredict” algorithm.

Promoter sequences Genome GC Total predictions (−500 to +500 w.r.t TSS at ‘0’) TP (−500 to 100) GC% in TP region TP genes Recall
S. cerevisiae 4912 38.3 11227 6312 37.6 4182 85.1
C. elegans 18457 35.4 28823 23063 35.1 16178 87.7
D. melanogaster 12898 42.1 18332 16232 39.8 11856 91.9
Zebrafish 5366 36.1 8220 5464 37.6 4313 80.4
Mouse 17451 41.9 22017 14281 54.6 11721 67.2
Human 29456 40.9 43043 27138 53.1 21009 71.3

Predictions in −500 to +500 regions w.r.t TSS of S. cerevisiae, C. elegans and D. Melanogaster, zebrafish, mouse and human have been carried out. PromPredict performs better in the case of yeast and invertebrates as compared to mammals. The −500 to +100 region relative to TSS is considered as true positive region.