Fig. 1.

Representative brain axial PET images of ¹⁸F-FPYBF-2 PET in a healthy volunteer and a patient with Alzheimer disease. The upper half showed a typical case of healthy 73 years old male volunteer, who has MMSE: 28 with Mean Cortical Index of SUVR as 0.977. The lower half showed a typical case of patient with Alzheimer disease, 65 years old male, who has MMSE: 14 with Mean Cortical Index of SUVR as 1.591. Prominent accumulation of ¹⁸F-FPYBF-2 was observed in gray matter of frontotemporal cortex, parietal and occipital cortex and posterior cingulate gyrus