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. 2018 Mar 14;8:4542. doi: 10.1038/s41598-018-22733-8

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Renal fibrosis at 52 weeks of age. (A) Glomerulosclerosis score with representative photomicrographs of PAS-stained glomeruli. (B) mRNA expression analysis of collagen I in renal cortical tissue. UNX d1, uninephrectomy at day 1 of life. UNX d14, uninephrectomy at day 14 of life. Co, control group with two kidneys. n = 8 for UNX d1, n = 7 for UNX d14, n = 8 for controls. Data are mean ± SEM. *p < 0.05 (one-way ANOVA, followed by Bonferroni post hoc test).