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. 2018 Mar 14;9(3):402. doi: 10.1038/s41419-018-0434-z

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a, b Western blotting was performed in HCT116 and SW480 cells to determine the change in EMT markers expression upon gain/loss function of TRIP13. The signal intensity and quantitative analysis are as shown. The values indicate the mean ± standard deviation. *p < 0.05; **p < 0.01; ***p < 0.001. c MS analysis of TRIP13-associated proteins. Cell lysate extract from Flag-tagged TRIP13-expressing or control was subjected to IP, and then, the IP complex was subjected to MS analysis. d GO analysis was performed to determine the biological processes in which TRIP13-interacting genes are involved. e The interaction network of TRIP13-interacting genes from STRING database