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. 2018 Mar 14;9(3):402. doi: 10.1038/s41419-018-0434-z

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — a Western blotting of EMT markers, TRIP13 and YWHAZ were performed in TRIP13 overexpressing CRC cells which transfected with siRNAs targeting YWHAZ, to determine whether TRIP13 mediates EMT in a YWHAZ dependent way. b, c The effect of knockdown of YWHAZ in TRIP13 overexpressing CRC cells on migration (b), and invasion (c). d YWHAZ IHC scores of the staining intensity level in representative tumor tissues. The bars are as indicated. e Spearman correlation coefficient plots for TRIP13 and YWHAZ. r = 0.532, 95%CI: (0.421–0.627), p < 0.001