Table 2.
Univariate and multivariate analysis of factors associated with overall survival in CRC patients
| Features | Overall survival | |||
|---|---|---|---|---|
| Univariate | Multivariate | |||
| p-value | HR | 95% CI | p-value | |
| Age: ≥60 vs. <60 years | 0.295 | NA | ||
| Gender: male vs. female | 0.276 | NA | ||
| Tumor location: colon vs. rectal | 0.394 | NA | ||
| Differentiation: poor vs. moderate & well | 0.882 | NA | ||
| Tumor size: ≥15 vs. <15 cm3 | 0.063 | NA | ||
| pTNM: I–II vs. III–IV | <0.001*** | 3.391 | 2.291–5.019 | <0.001*** |
| CEA: ≥5 vs. <5 ug/l | <0.001*** | 1.7 | 1.2–2.406 | 0.03* |
| CA125: ≥35 vs. <35 U/ml | 0.153 | NA | ||
| CA19-9: ≥37 vs. <37 U/ml | 0.003** | NS | ||
| TRIP13: high vs. low | <0.001*** | 1.887 | 1.321–2.696 | <0.001*** |
NA not adopted, NS not significant. *p < 0.05; **p < 0.01; ***p < 0.001