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. 2018 Feb 23;7(3):726–735. doi: 10.1002/cam4.1369

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© 2018 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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The prognostic values of the 5‐miRNA signature in HNSCC patients with/without RT. (A) Kaplan–Meier analysis of overall survival in 509 patients according to the 5‐miRNA signature. It was observed that the 5‐miRNA signature also had a significant prognostic value in all of 509 HNSCC patients with or without RT. (B) Kaplan–Meier survival analysis in different subgroups of clinical characteristics according to the 5‐miRNA signature. The 5‐miRNA signature was capable of predicting the OS in different clinicopathological factors. (C) Kaplan–Meier survival in 5‐miRNA signature‐based risk group according to patients with/without RT, who were stratified by different clinical characteristics. We calculated P values using the log‐rank test. We found in different subgroups, only low‐risk group could get benefit in receiving RT, but high‐risk group had similar survival with or without RT.