Fig. 6.

Association between increased prefrontal-premotor-M1 coupling and behavioural performance.

When controlling for grey matter atrophy as informed by the VBM analysis, increased net coupling within the prefrontal-premotor-M1 axis (PFC-PMC + SMA-M1 connectivity) negatively correlates with RTs in both the ‘Intern’ and ‘Extern’ condition. Hence, stronger positive coupling is associated with faster RT, i.e., better behavioural performance. Note that in both panels, data points of two subjects are very close, giving rise to the impression that the plots only contain 11 data points. However, in conformity with previous figures, all 12 data points are displayed in both panels. PFC = prefrontal cortex, PMC = premotor cortex, SMA = supplementary motor area, M1 = primary motor cortex, IPS = intraparietal sulcus. *p < 0.05, FDR-corrected for multiple comparisons.