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. 2018 Feb 20;11(2):366–373. doi: 10.1016/j.tranon.2018.01.024

Figure 4.

Figure 4

C3-Fc induced NK cell–mediated cytotoxicity. (A) The cytotoxic activities of C3-Fc were dependent on the presence of NK cells. Different cell lines were treated with C3-Fc with or without fresh isolated NK cells. (B) Dose-dependent cytotoxicity assays were performed with human NK cells as effector cells and CHO, MCF7, LS174T, and SKOV3 as target cells (E/T=10:1) in the presence of Her2-Fc proteins. The concentration of Her2-Fc was from 150 nM to 0.0015 nM. The mixtures were incubated for 72 hours before the cytotoxicity measurement. All the data are the mean of triplicates, with the error bars representing the standard deviation.