BOS-102 inhibits the viability, migration, and colony formation in human cancer cell lines. (A) The inhibitory effect of BOS-102 on the cell proliferation of A549, HepG2, U87 MG, and PANC-1 cells. Cells were treated with various concentrations of BOS-102 (0, 3, 6, 12, 24 µM) for 48 h. After incubation, cell viability was evaluated by MTT assay; (B,C) A549 cells were treated with BOS-102 (0, 2.5, 5, 10 µM) for 10 day and colony formation was determined by staining with crystal violet. The data represent mean values (±SD) obtained from three separate experiments. ** p < 0.01 vs. control group.