Table 2.
Effect of low-dose Ang II combined with regular or 2% high salt diet on heart rate, RV weight, BW gain, water intake and plasma electrolytes
| Regular salt | High salt | Regular salt + Ang II | High salt + Ang II | |
|---|---|---|---|---|
| HR (bpm) | 444 ± 11 | 421 ± 10 | 441 ± 14 | 433 ± 15 |
| RV weight (mg/100g BW) | 47 ± 3 | 45 ± 2 | 49 ± 2 | 52 ± 2 |
| BW gain (g) | 79 ± 5 | 70 ± 4 | 78 ± 4 | 82 ± 4 |
| Water intake (ml/100g BW) | ||||
| End of first week | 14 ± 1 | 17 ± 1 | 14 ± 1 | 21 ± 1* |
| End of second week | 12 ± 1 | 15 ± 1** | 12 ± 1 | 19 ± 1* |
| Plasma Na+ (mmol/L) | 144 ± 1 | 146 ± 1 | 145 ± 1 | 142 ± 1 |
| Plasma K+ (mmol/L) | 5.1 ± 0.2 | 5.6 ± 0.1 | 5.2 ± 0.1 | 5.1 ± 0.2 |
| Plasma Cl− (mmol/L) | 100 ± 1 | 103 ± 1 | 101 ± 1 | 101 ± 1 |
Values are means ± SE. For HR, BW gain and water intake, n = 12–16/group (2 studies combined). For RV weight, n = 8–13/group (preliminary experiment + first study of first experiment). For Na+, K+ and Cl−, n = 6–10/group.
HR, heart rate;RV, right ventricle; BW, body weight.
*
P < 0.05 vs. others.
**
P < 0.05 vs. regular salt.