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. 2017 Aug 29;113(13):1688–1699. doi: 10.1093/cvr/cvx167

Figure 5.

Figure 5

β-adrenergic stimulation suppresses TCWs in NAMs but has little effect in HFAMs. (A) Example of a NAM before and during exposure to isoproterenol (ISO). Dashed box indicates presence of CaT alternans. (B) Example of ISO effects in an HFAM. (C i) Summary of ISO action on TCW incidence in NAMs vs. HFAMs at 3.3–5 Hz; (ii) F/F0 and change in F/F0 with ISO (1 Hz); (iii) CaT 90–10% decay time and change in decay time with ISO (1 Hz). n = 16 NAMs from six atria; n = 43 HFAMs from nine atria. **P < 0.01; ***P < 0.001 between ISO and Control. †P < 0.05, ††P < 0.01, †††P < 0.001; §§P < 0.01, §§§P < 0.001 between NAMs and HFAMs using two-way ANOVA or unpaired and paired t-tests.