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CCh and ranolazine suppress TCWs. (A) Effects of CCh on TCWs in a NAM before, during and after washout during constant pacing at 3.3 Hz. (B) Summary of effects of CCh (n = 21 NAMs from five normal atria). ***P < 0.001 (paired t-test). (C) Actions of ranolazine on TCWs. Typical linescan recording of a NAM before and during a brief exposure to 10 µM ranolazine. (D) Summary of TCW incidence before and after ranolazine (n = 6 NAMs from three normal atria). *P < 0.05 (paired t-test).
