Table 2.
Representative miRNAs involved in cancer diseases and covered in this review.
| miRNA | Target | Biologic Function | Reference |
|---|---|---|---|
| Let-7 | c-myc, HMGA2, RAS | Tumour suppressor | [163,171] |
| miR-10b | HOXD10 | Oncogene | [172] |
| miR-21 | PTEN, TPM1, PDCD4 | Oncogene | [173] |
| miR-122a | Cyclin G1 | Tumour suppressor | [174] |
| miR-155 | AT1R, TP53INP1 | Oncogene | [175] |
| miR-210 | HIF-1α | Oncogene | [176] |
| miR-221/222 | CD117 | Oncogene | [177] |
| miR-205 | PRKCε | Tumour suppressor | [178] |
| miR-20a | TIMP2, ATG7 | Oncogene | [179] |
| miR-29b | Mcl-1 | Oncogene | [180] |
| miR-712 | TIMP3 | Oncogene | [181,182] |