Type of alternative splicing	TFs	Effects on TF
Exon skipping/retention	NFIX1/2/3	NFIX2: regulator of fetal muscle genes
	HEBα/β	HEBα: higher DNA binding and transcriptional activity HEBβ: synergises with MyoD in early differentiation
	PAX3Q+/−	PAX3Q-: stronger binding affinity and higher transcriptional activity
	PAX7Q+/−	NA
	PAX7GL+/−	PAX7GL-: increased binding affinity
	PAX7-2	PAX7-2: reduced transcriptional activity
	E12/47 E2A-2/5	E2A-2/5: dominant negative activity
	MEF2A/B/C β	MEF2A/B/C β: higher transcriptional activity
	TCF4 A-R	TCF4 AD1-containing isoforms: higher transcriptional activity
	TCF4 FL/Δ	TCF4 FL/Δ: no correlation with transcriptional activity
Intron retention	TMyoD1α/β	NA
	ID1A/B	ID1A: inhibits the formation of E12/MYOD heterodimers. ID1B: prevents the assembly of E12/E12 homodimers.
	ID3/3L	ID3L: reduced antagonistic activity versus E47
Mutually exclusive exons	MEF2A/B/C α1/α2	MEF2A/B/C α1: repressor of terminal differentiation MEF2A/B/C α2: activator of terminal differentiation
	TCF4 A-R	TCF4 AD1-containing isoforms: higher transcriptional activity
Alternative 5’ or 3’ splice site usage	TCF4 A-R −/+	TCF4 -/+: no correlation with transactivation activity
	MEF2C γ	MEF2C γ: reduced transcriptional activity
Alternative 3’ terminal exon	CiMDFa/b	CiMDFb: higher myogenic effector function
	PAX7A/B	PAX7A/B: myogenic commitment
	PAX3A/B	NA
	PAX3C/D	PAX3C: necessary for terminal myogenic differentiation PAX3D: maintenance and/or proliferation of muscle precursor
Premature termination codon (PTC)	TMyoD1γ	TMyoD1γ: role in the regulation of TmyoD1 expression