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. 2017 Mar 23;113(10):1124–1136. doi: 10.1093/cvr/cvx060

Figure 2.

Figure 2

Mild disease phenotype in 5–6 month-old E143K mice. Assessment of heart morphology and function in E143K vs. WT mice by echocardiography (A) and invasive haemodynamics (B). Abbreviations: HW/BW, heart weight/body weight in mg/g; EF%, ejection fraction; IVS, inter ventricular septum in diastole (d) and systole (s); LVID, left ventricular inner diameter; LVPW, left ventricular posterior wall; SW, stroke work; CO, cardiac output; SV, stroke volume; EDV, end-diastolic volume; Ped, end-diastolic pressure; Tau, relaxation time constant; ESPVR, end-systolic PV relation (slope); EDPVR, end-diastolic PV relation (slope) and PRSW, pre-load recruitable power stroke work. F-female (open symbols); M-male (closed symbols) mice. Data expressed as mean ± SEM; t-test, *P < 0.05, **P < 0.01 vs. WT.