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. 2017 Mar 23;113(10):1124–1136. doi: 10.1093/cvr/cvx060

Figure 7.

Figure 7

Protein expression changes in E143K vs. WT hearts. (A) Biological processes affected in E143K animals. A total of 43 proteins had differential expression in E143K-hearts compared with WT. The major differentially expressed proteins are those involved in metabolic processes. (B) Proteins related to mitochondrial content and ATP production that were differentially expressed in E143K vs. WT mice. # indicates a downregulated protein vs. all other upregulated proteins. (C) Western blot and (D) Quantification of VDAC1 expression confirming proteomic data. Data are mean ± SEM, t-test, *P < 0.05 vs. WT.