Table 3.
Almond Treatments, % of Sequences 1 | ||||||
---|---|---|---|---|---|---|
Control 0 g/Day | Almond Butter 42 g/Day | Chopped Almonds 42 g/Day | Whole Roasted 42 g/Day | Whole Raw 42 g/Day | p-Value | |
PhylaandGenera | ||||||
Firmicutes | 63.9 ± 1.99 | 64.2 ± 1.99 | 66.2 ± 2.13 | 66.2 ± 1.99 | 66.1 ± 2.03 | 0.68 |
Faecalibacterium | 4.39 ± 0.68 | 4.62 ± 0.68 | 4.48 ± 0.70 | 4.40 ± 0.68 | 4.94 ± 0.68 | 0.63 |
Coprococcus | 4.54 ± 0.54 | 4.60 ± 0.54 | 4.51 ± 0.56 | 5.06 ± 0.54 | 4.59 ± 0.54 | 0.73 |
Ruminococcus | 4.65 ± 0.70 | 4.73 ± 0.69 | 3.70 ± 0.73 | 4.22 ± 0.69 | 3.88 ± 0.70 | 0.39 |
Blautia | 2.09 ± 0.33 | 2.07 ± 0.33 | 2.36 ± 0.34 | 2.37 ± 0.33 | 2.24 ± 0.33 | 0.63 |
Dorea | 1.61 ± 0.28 | 1.71 ± 0.28 | 1.67 ± 0.29 | 1.77 ± 0.28 | 1.58 ± 0.29 | 0.87 |
Phascolarctobacterium 2 | 0.23 ± 0.29 | 0.24 ± 0.29 | 0.23 ± 0.29 | 0.20 ± 0.29 | 0.19 ± 0.29 | 0.70 |
Roseburia 2 | 0.47 ± 0.14 | 0.48 ± 0.14 | 0.83 ± 0.14 * | 0.73 ± 0.14 ^ | 0.73 ± 0.14 ^ | <0.01 |
Lachnospira 2 | 0.49 ± 0.15 | 0.54 ± 0.15 | 0.80 ± 0.15 * | 0.79 ± 0.15 * | 0.76 ± 0.15 ^ | 0.02 |
Dialister | 0.42 ± 0.31 | 0.44 ± 0.31 | 0.70 ± 0.32 | 0.74 ± 0.31 | 1.03 ± 0.31 * | 0.01 |
Clostridium 2 | 0.42 ± 0.08 | 0.52 ± 0.08 | 0.54 ± 0.09 | 0.58 ± 0.08 | 0.48 ± 0.08 | 0.24 |
Streptococcus 2 | 0.17 ± 0.18 | 0.23 ± 0.18 | 0.17 ± 0.18 | 0.18 ± 0.18 | 0.11 ± 0.18 | 0.09 |
Oscillospira | 0.54 ± 0.07 | 0.54 ± 0.07 | 0.75 ± 0.07 * | 0.53 ± 0.07 | 0.51 ± 0.07 | 0.02 |
Bacteroidetes | 25.7 ± 2.13 | 27.1 ± 2.14 | 26.5 ± 2.30 | 25.7 ± 2.14 | 27.6 ± 2.19 | 0.90 |
Bacteroides | 19.2 ± 2.15 | 20.8 ± 2.15 | 20.4 ± 2.26 | 19.6 ± 2.15 | 20.6 ± 2.18 | 0.88 |
Parabacteroides | 1.31 ± 0.23 | 1.07 ± 0.23 | 0.89 ± 0.23 | 1.03 ± 0.23 | 0.93 ± 0.23 | 0.13 |
Prevotella 2 | 0.03 ± 0.31 | 0.03 ± 0.31 | 0.04 ± 0.31 | 0.04 ± 0.31 | 0.03 ± 0.31 | 0.75 |
Actinobacteria | 5.45 ± 1.05 | 4.51 ± 1.06 | 3.77 ± 1.11 | 4.09 ± 1.06 | 3.20 ± 1.07 | 0.16 |
Bifidobacterium | 3.68 ± 0.85 | 2.68 ± 0.85 | 2.71 ± 0.89 | 2.53 ± 0.85 | 2.04 ± 0.86 | 0.19 |
Collinsella 2 | 0.14 ± 0.24 | 0.12 ± 0.24 | 0.12 ± 0.25 | 0.16 ± 0.24 | 0.13 ± 0.24 | 0.87 |
Verrucomicrobia | 1.45 ± 0.34 | 1.16 ± 0.34 | 1.10 ± 0.36 | 1.25 ± 0.34 | 0.87 ± 0.35 | 0.44 |
Akkermansia | 1.45 ± 0.34 | 1.16 ± 0.34 | 1.10 ± 0.36 | 1.25 ± 0.34 | 0.87 ± 0.35 | 0.44 |
Proteobacteria | 2.34 ± 0.51 | 1.93 ± 0.51 | 1.88 ± 0.55 | 1.75 ± 0.51 | 1.29 ± 0.52 | 0.45 |
n = 18 | n = 18 | n = 15 | n = 18 | n = 17 |
1 Values are least-square means ± pooled SEM; n = 15–18 participants in a crossover design. 2 Values are mean log-normalized sequence abundances ± SE. Treatment effects of genera representing ≥0.5% of the total sequences were evaluated by using a mixed-model ANOVA with post-hoc Dunnet’s adjustments for multiple comparisons. Comparisons were made to the control condition. * p ≤ 0.05 for comparison between the respective treatment condition and control condition; ^ p ≤ 0.1 for comparison between the respective treatment condition and control condition.