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. 2018 Feb 16;10(2):219. doi: 10.3390/nu10020219

Figure 2.

Figure 2

ZIP4 and ZIP10 support p63 activity for adult epidermal homeostasis. ZIP4 and ZIP10 supply zinc to epidermal master regulator p63 for their activity. Zinc deficiency leads to improper function of p63, resulting in epidermal hypoplasia. Zinc is depicted as a brown circle.