Table 4.
Childhood adversities as predictors of SF-36 physical component summary (PCS) score: results from bivariable and multivariable linear regression models.
Predictor variable | Bivariable regression model | Multivariable regression model | ||||
---|---|---|---|---|---|---|
β | (95% CI) | p | β | (95% CI) | p | |
Number of childhood adversity | ||||||
Five to seven | −4.46 | (−6.17, −2.74) | <0.001 | −3.68 | (−5.49, −1.88) | <0.001 |
Four | −0.71 | (−2.21,0.79) | 0.354 | −0.93 | (−2.52,0.65) | 0.248 |
Three | 0.69 | (−0.69,2.06) | 0.330 | 0.61 | (−0.85,2.07) | 0.413 |
Two | −0.38 | (−1.51,0.76) | 0.518 | −0.40 | (−1.64,0.84) | 0.524 |
One | 0.47 | (−0.55,1.49) | 0.364 | −0.03 | (−1.16,1.09) | 0.953 |
None (ref) | 0 | - | - | 0 | - | - |
Age in years | ||||||
>50 | −2.36 | (−3.25, −1.48) | <0.001 | −3.59 | (−5.56, −1.62) | <0.001 |
41–50 | 0.27 | (−0.66,1.19) | 0.572 | −2.42 | (−4.27, −0.57) | <0.001 |
31–40 | 1.93 | (0.74,3.12) | 0.002 | −1.17 | (−3.08,0.74) | 0.230 |
≤30 (ref) | 0 | - | - | 0 | - | - |
Sex/gender | ||||||
Female | −0.58 | (−1.69,0.53) | 0.303 | −0.39 | (−1.78,1.00) | 0.584 |
Male, MSM | 1.08 | (0.17,1.99) | 0.020 | 1.14 | (−0.07,2.34) | 0.064 |
Male, non-MSM (ref) | 0 | - | - | 0 | - | - |
Race/ethnicity | ||||||
Indigenous | −2.17 | (−4.11, −0.23) | 0.028 | −0.63 | (−2.48,1.22) | 0.503 |
African/Caribbean/Black | 1.00 | (−0.03,2.02) | 0.057 | 0.04 | (−1.55,1.63) | 0.962 |
Other, non-White | 0.23 | (−1.02,1.48) | 0.717 | −0.95 | (−2.40,0.50) | 0.198 |
White (ref) | 0 | - | - | 0 | - | - |
Education | ||||||
Less than HS completion | −3.24 | (−4.61, −1.88) | <0.001 | −1.53 | (−3.05,0.00) | 0.050 |
Completed high school | −1.38 | (−2.51, −0.24) | 0.017 | −1.17 | (−2.42,0.09) | 0.070 |
Some postsecondary | 0.34 | (−0.57,1.24) | 0.465 | −0.82 | (−1.84,0.20) | 0.113 |
Completed University (ref) | 0 | - | - | 0 | - | - |
Born in Canada | ||||||
Yes | −1.34 | (−2.22, −0.45) | 0.003 | −1.33 | (−2.58, −0.09) | 0.036 |
No (ref) | 0 | - | - | 0 | - | - |
Currently employed | ||||||
Yes | 4.75 | (3.91,5.60) | <0.001 | 3.34 | (2.45,4.23) | <0.001 |
No (ref) | 0 | - | - | 0 | - | - |
Hazardous alcohol use | ||||||
Yes | 1.45 | (0.50,2.39) | 0.003 | 1.03 | (0.11,1.94) | 0.029 |
No (ref) | 0 | - | - | 0 | - | - |
Cigarette smoking | ||||||
Current smoker | −1.85 | (−2.82, −0.88) | <0.001 | −1.24 | (−2.31, −0.17) | 0.024 |
Former smoker | −0.67 | (−1.70,0.36) | 0.205 | −0.83 | (−1.91,0.25) | 0.131 |
Never smoker (ref) | 0 | - | - | 0 | - | - |
Nonmedicinal drug use | ||||||
Yes | −0.28 | (−1.61,1.06) | 0.683 | - | - | - |
No (ref) | 0 | - | - | - | - | - |
Duration of HIV infection | ||||||
Years (per 10 years) | −1.81 | (−2.35, −1.27) | <0.001 | −0.68 | (−1.31, −0.04) | 0.036 |
Diagnosed with AIDS | ||||||
Yes | −1.96 | (−2.84, −1.07) | <0.001 | −0.83 | (−1.69,0.03) | 0.057 |
No (ref) | 0 | - | - | 0 | - | - |
Recent CD4 count (cells/mm 3) | ||||||
≥500 | 1.19 | (0.31,2.07) | 0.008 | 1.41 | (−0.24,3.06) | 0.093 |
200–499 | −0.40 | (−1.29,0.49) | 0.382 | 1.08 | (−0.58,2.73) | 0.202 |
<200 (ref) | 0 | - | - | 0 | - | - |
HIV viral load (copies/mL) | ||||||
≥50 | −1.17 | (−2.28, −0.07) | 0.037 | −0.98 | (−2.07,0.11) | 0.079 |
<50 (ref) | 0 | - | - | 0 | - | - |
Bold face indicates statistical significance (p < 0.05). Note. Variables with p < 0.10 in bivariable regression models were included in the multivariable regression model. The final multivariable model is further adjusted for mastery, social support, coping, and stress.