Table 2.
Subnetwork | Pathway ID | Pathway name | Count | p value | Genes |
---|---|---|---|---|---|
Subnetwork a | hsa04080 | Neuroactive ligand-receptor interaction | 5 | 1.40E−04 | MCHR1, PTGER3, S1PR5, FPR3, NPY1R |
hsa04062 | Chemokine signaling pathway | 3 | 1.80E−02 | CCR9, CCR6, CCR4 | |
hsa04060 | Cytokine-cytokine receptor interaction | 3 | 2.74E−02 | CCR9, CCR6, CCR4 | |
Subnetwork c | hsa04110 | Cell cycle | 6 | 1.31E−04 | CCNB1, CDC14A, PRKDC, CCNA2, MCM4, TFDP1 |
hsa05416 | Viral myocarditis | 4 | 1.62E−03 | ICAM1, CASP8, HLA-C, CD40 | |
hsa05168 | Herpes simplex infection | 5 | 6.03E−03 | SP100, CASP8, OAS3, PML, HLA-C | |
hsa04514 | Cell adhesion molecules | 4 | 1.70E−02 | VCAM1, ICAM1, HLA-C, CD40 | |
hsa05144 | Malaria | 3 | 1.78E−02 | VCAM1, ICAM1, CD40 | |
hsa04621 | NOD-like receptor signaling pathway | 3 | 2.00E−02 | CASP8, RIPK2, CASP1 | |
hsa04115 | p53 signaling pathway | 3 | 2.93E−02 | CCNB1, RRM2, CASP8 | |
hsa05164 | Influenza A | 4 | 3.32E−02 | ICAM1, OAS3, PML, CASP1 | |
hsa04914 | Progesterone-mediated oocyte maturation | 3 | 4.30E−02 | CCNB1, GNAI2, CCNA2 | |
hsa05169 | Epstein–Barr virus infection | 4 | 4.42E−02 | ICAM1, HLA-C, CD40, CCNA2 | |
hsa05203 | Viral carcinogenesis | 4 | 4.60E−02 | SP100, CASP8, HLA-C, CCNA2 | |
hsa04064 | NF-kappa B signaling pathway | 3 | 4.84E−02 | VCAM1, ICAM1, CD40 |
KEGG, Kyoto Encyclopedia of Genes and Genomes.