Table 3.
Overall outcomes of the meta-analysis.
| Outcomes | Studies No. | Sample size | Heterogeneity (P, I2) |
Model | Overall effect size | 95% CI of overall effect | P | |
|---|---|---|---|---|---|---|---|---|
| LH | OH | |||||||
| Operation time (min) | 20 | 1255 | 1671 | <0.01, 87% | R | WMD = 9.15 | −7.61~25.90 | 0.28 |
| Minor hepatectomy | 8 | 321 | 355 | <0.01, 78% | R | WMD = 12.04 | −5.31~29.39 | 0.17 |
| Mixed hepatectomy | 9 | 831 | 1213 | <0.01, 83% | R | WMD = −14.28 | −40.76~12.21 | 0.29 |
| Major hepatectomy | 3 | 103 | 103 | 0.05, 67% | R | WMD = 77.93 | 40.45~115.41 | <0.01 |
| Blood loss (mL) | 17 | 1128 | 1425 | <0.01, 92% | R | WMD = −93.21 | −157.33~−29.09 | <0.01 |
| Minor hepatectomy | 7 | 278 | 312 | 0.39, 5% | R | WMD = −76.21 | −98.41~−54.01 | <0.01 |
| Mixed hepatectomy | 7 | 747 | 1010 | 0.05, 52% | R | WMD = −212.94 | −294.57~−131.31 | <0.01 |
| Major hepatectomy | 3 | 103 | 103 | 0.88, 0% | R | WMD = 3.75 | −60.16~67.65 | 0.88 |
| Transfusion | 14 | 979 | 1352 | 0.90, 0% | F | RR = 0.73 | 0.55~0.96 | 0.03 |
| Minor hepatectomy | 4 | 121 | 155 | 0.49, 0% | F | RR = 0.53 | 0.19~1.45 | 0.22 |
| Mixed hepatectomy | 8 | 788 | 1127 | 0.86, 0% | F | RR = 0.75 | 0.55~1.01 | 0.06 |
| Major hepatectomy | 2 | 70 | 70 | 0.28, 15% | F | RR = 0.75 | 0.17~3.25 | 0.70 |
| Hospital stay (days) | 20 | 1255 | 1671 | <0.01, 80% | R | WMD = −2.86 | −3.63~−2.08 | <0.01 |
| Minor hepatectomy | 8 | 321 | 355 | <0.01, 76% | R | WMD = −2.93 | −4.23~−1.63 | <0.01 |
| Mixed hepatectomy | 9 | 831 | 1213 | 0.01, 58% | R | WMD = −2.85 | −3.95~−1.76 | <0.01 |
| Major hepatectomy | 3 | 103 | 103 | 0.15, 47% | R | WMD = −2.76 | −4.60~−0.92 | <0.01 |
| Morbidity | 20 | 1255 | 1671 | 0.28, 14% | F | RR = 0.55 | 0.47~0.65 | <0.01 |
| Minor hepatectomy | 8 | 321 | 355 | 0.29, 17% | F | RR = 0.53 | 0.41~0.69 | <0.01 |
| Mixed hepatectomy | 9 | 831 | 1213 | 0.26, 21% | F | RR = 0.57 | 0.46~0.72 | <0.01 |
| Major hepatectomy | 3 | 103 | 103 | 0.21, 37% | F | RR = 0.55 | 0.36~0.83 | <0.01 |
| Severe complications | 18 | 1196 | 1476 | 0.88, 0% | F | RR = 0.51 | 0.39~0.68 | <0.01 |
| Minor hepatectomy | 7 | 288 | 305 | 0.96, 0% | F | RR = 0.48 | 0.24~0.96 | 0.04 |
| Mixed hepatectomy | 8 | 805 | 1068 | 0.44, 0% | F | RR = 0.54 | 0.38~0.76 | <0.01 |
| Major hepatectomy | 3 | 103 | 103 | 0.35, 6% | F | RR = 0.42 | 0.18~1.00 | 0.05 |
| Mortality | 9 | 789 | 1026 | 0.88, 0 | F | RR = 0.43 | 0.18~1.00 | 0.05 |
| Minor hepatectomy | 3 | 104 | 121 | 0.34, 7 | F | RR = 0.39 | 0.09~1.68 | 0.21 |
| Mixed hepatectomy | 5 | 653 | 873 | 0.84, 0 | F | RR = 0.46 | 0.15~1.43 | 0.18 |
| Major hepatectomy | 1 | 32 | 32 | Not applicable | F | RR = 0.33 | 0.01~7.89 | 0.50 |
| Tumor size (cm) | 19 | 1229 | 1645 | <0.01, 57% | R | WMD = −0.19 | −0.41~0.03 | 0.09 |
| Minor hepatectomy | 8 | 321 | 355 | 0.76, 0% | R | WMD = −0.07 | −0.26~0.12 | 0.48 |
| Mixed hepatectomy | 8 | 805 | 1187 | 0.50, 0% | R | WMD = −0.09 | −0.25~0.07 | 0.28 |
| Major hepatectomy | 3 | 103 | 103 | <0.01, 92% | R | WMD = −1.77 | −4.06~0.53 | 0.13 |
| Margin distance (cm) | 11 | 501 | 694 | 0.14, 47% | R | WMD = 2.61 | 1.06~4.17 | <0.01 |
| Minor hepatectomy | 5 | 186 | 220 | 0.06, 56% | R | WMD = 2.16 | 0.15~4.17 | 0.03 |
| Mixed hepatectomy | 5 | 282 | 441 | 0.15, 41% | R | WMD = 3.20 | 0.41~5.99 | 0.02 |
| Major hepatectomy | 1 | 33 | 33 | Not applicable | R | WMD = 5.90 | −2.69~14.49 | 0.18 |
| R0 resection | 14 | 1010 | 1409 | 0.70, 0% | F | RR = 1.01 | 0.99~1.02 | 0.37 |
| Minor hepatectomy | 6 | 240 | 257 | 0.80, 0% | F | RR = 0.98 | 0.95~1.01 | 0.23 |
| Mixed hepatectomy | 7 | 738 | 1120 | 0.47, 0% | F | RR = 1.01 | 1.00~1.03 | 0.13 |
| Major hepatectomy | 1 | 32 | 32 | Not applicable | F | RR = 1.03 | 0.93~1.15 | 0.56 |
WMD: weighted mean difference; RR: risk ratio; F: fixed; R: random.