Table 1.
Demographic data of the included patients
| Characteristics | All patients (N = 24) |
|---|---|
| Male sex, n (%) | 14 (61) |
| Age, years | 53 ± 17 |
| Comorbidities, n (%) | |
| Arterial hypertension | 3 (13) |
| Diabetes mellitus | 5 (21) |
| Tobacco use | 2 (10) |
| Others | 3 (13) |
| Origin of patients, n (%) | |
| Emergency room | 12 (50) |
| Ward | 5 (21) |
| Operating room | 7 (29) |
| Source of sepsis, n (%) | |
| Lung | 7 (28) |
| Urinary | 5 (21) |
| Abdominal | 5 (21) |
| Other sources | 5 (21) |
| Undetermined | 2 (8) |
| Hemodynamic data | |
| Norepinephrine dosage D0, μg/kg/minute | 0.3 (0.1–0.5) |
| Lactate D0, mg/dl | 22 (18–36) |
| Mean arterial pressure D0, mmHg | 70 (63–78) |
| Ventilatory data | |
| Use of mechanical ventilation D0, n (%) | 16 (67) |
| Tidal volume D0, ml | 500 ± 88 |
| PEEP D0, cmH2O | 8 ± 2.7 |
| Fraction of inspired oxygen | 0.4 ± 0.17 |
| Peripheral oxygen saturation D0, % | 96 ± 2 |
| Duration of mechanical ventilation, days | 3 (2.25–7) |
| Hematologic and inflammatory data | |
| Leukocytes D0, cells/mm3 | 18,974 ± 9790 |
| Leukocytes D7, cells/mm3 | 13,270 ± 6262 |
| Hemoglobin D0, g/dl | 10.4 ± 1.6 |
| Hemoglobin D7, g/dl | 9.7 ± 1.7 |
| Platelets D0, 103 cells/mm3 | 185 ± 134 |
| Platelets D7, 103 cells/mm3 | 261 ± 114 |
| CRP D0 (n = 18), mg/dl | 290 (212–327) |
| CRP D7 (n = 17), mg/dl | 51 (30–125) |
| Procalcitonin D0 (n = 9), ng/ml | 15.7 (2–22.4) |
| SAPS3 score | 57.7 ± 6.2 |
| SOFA score D0 | 8.4 ± 3.3 |
| SOFA score D7 | 1.7 ± 3.8 |
| ICU length of stay, days | 5 (4–7.75) |
| Hospital length of stay, days | 13.5 (8–22.5) |
| Hospital mortality, n (%) | 8 (35) |
Abbreviations: PEEP Positive end-expiratory pressure, CRP C-reactive protein, SAPS3 Simplified Acute Physiology Score III, SOFA Sequential Organ Failure Assessment, ICU Intensive care unit
Data are expressed as number (%), mean ± SD, or median (25th–75th percentile)