Table 2.
Overall survival analyses for CN-AML patients
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| P value | HR (95%) | P value | HR (95%) | |
| miR-362-5p | 0.028 | 1.615 (1.048, 2.488) | 0.045 | 1.599 (1.011, 2.528) |
| WBC | < 0.001 | 1.005 (1.003, 1.008) | < 0.001 | 1.006 (1.003, 1.009) |
| Hemoglobin | 0.242 | 0.995 (0.987, 1.003) | 0.297 | 0.995 (0.987, 1.004) |
| Age | 0.006 | 1.02 (1.006, 1.035) | 0.005 | 1.022 (1.007, 1.038) |
| FLT3-ITD | 0.654 | 1.136 (0.65, 1.987) | 0.723 | 1.11 (0.622, 1.982) |
| CEBPADM& | 0.014 | 0.352 (0.153, 0.809) | 0.007 | 0.312 (0.133, 0.732) |
| NPM1 | 0.884 | 1.038 (0.629, 1.712) | 0.039 | 0.547 (0.309, 0.969) |
| DNMT3A | 0.157 | 1.58 (0.838, 2.979) | 0.356 | 1.376 (0.699, 2.711) |
| IDH1 | 0.043 | 1.879 (1.019, 3.466) | 0.125 | 1.662 (0.868, 3.183) |
| IDH2 | 0.613 | 0.849 (0.45, 1.601) | 0.196 | 0.644 (0.331, 1.254) |
MiR-362-5p: high vs low expression, Age, WBC and hemoglobin are used as continuous variables
DM& double allele mutations