Table 3.

Antibody Levels (Optical Density) as a Function of Age, Sex, Human Immunodeficiency Virus Serostatus and Calendar Time^a (N = 9077^c)

Characteristic	K8.1 Log10 (OD)			ORF73 Log10 (OD)
	Coeff b	(95% CI)	P Value	Coeffb	(95% CI)	P Value
Age, y
0–14			<.001			<.001
15–24	0.39	(.33–.44)		0.43	(.37–.49)
25–44	0.43	(.37–.49)		0.53	(.47–.60)
≥45	0.55	(.49–.62)		0.79	(.73–.86)
Sex
Female	Ref			Ref
Male	0.18	(.13–.23)	<.001	0.09	(.04–.13)	<.001
Year
1992	Ref			Ref
2000	0.17	(.13–.22)	<.001	0.18	(.13–.23)	<.001
2008	–0.04	(–.09 to .00)	.067	–0.04	(–.08 to .01)	.151
HIV infected	–0.14	(–.24 to –.05)	.004	–0.15	(–.25 to –.06)	.002

Abbreviations: HIV, human immunodeficiency virus; OD, optical density.

^aHierarchical model accounting for individual and village clustering.

^bCoefficient adjusted for the other factors.

^cThirty-five biospecimen not available.