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. 2017 Dec 8;217(5):721–730. doi: 10.1093/infdis/jix639

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© The Author(s) 2017. Published by Oxford University Press for the Infectious Diseases Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — MG1 preferentially infects and eliminates cell lines latently infected with human immunodeficiency virus type 1 (HIV-1). A, The percentage of green fluorescent protein (GFP)–expressing (GFP+) cells 20 hours after MG1 infection, by flow cytometry (n = 8). Inset representative histograms show MG1 infection (GFP+ cells) of U1 cells latently infected with HIV and uninfected U937 cells 20 hours after MG1 infection. B, Percentage GFP+ cells following infection (multiplicity of infection [MOI], 0.005) at the indicated time points (n = 8). C, The percentage of viable cells 20 hours after MG1 infection, by the AlamarBlue assay (n = 8). D, The percentage of viable cells following MG1 infection (MOI, 0.005) over time (n = 8). *P < .05; **P < .01, and ***P < .001 by 2-way analysis of variance with the Bonferroni post hoc test for multiple comparisons between U937 and U1 cells. Data represent mean values ± standard errors of the mean; n values represent separate biological replicates.