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. 2017 Dec 8;217(5):721–730. doi: 10.1093/infdis/jix639

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© The Author(s) 2017. Published by Oxford University Press for the Infectious Diseases Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Elimination of replication-competent human immunodeficiency virus type 1 (HIV-1) in HIV-infected resting CD4⁺ T cells is prevented by UV light inactivation of MG1. A, Integrated HIV-1 DNA 48 hours after infection with MG1 that was or was not inactivated by UV light (n = ≥6). *P < .0001 by 1-way analysis of variance (ANOVA) on ranks, and P < .05 by the Dunn multiple comparison test. B, p24 concentration at day 10 of a viral outgrowth assay following infection with MG1 or UV light–inactivated MG1 (n = 4). *P = .0228 by 1-way ANOVA on ranks, and P < .05 by the Dunn multiple comparison test. Data points in panel B are the average of duplicate technical replicates. Data represent mean values ± standard errors of the mean; n values represent separate biological replicates. Individual donors are defined by color in panel B. MOI, multiplicity of infection; NS, not significant.