. 2017 Jul 28;216(6):651–661. doi: 10.1093/infdis/jix367

Table 1.

Odds Ratios for Mortality in Human Immunodeficiency Virus–Infected Infants by 6-Week Biomarker Levels

Biomarker	<25th Percentile (Ref)	25th–49th Percentile	50th–74th Percentile	≥75th Percentile
Biomarker	OR	OR (95% CI)	OR (95% CI)	OR (95% CI)
I-FABP (58 cases/119 controls)^a
Unadjusted	1.0	0.8 (.3–1.8)	0.6 (.3–1.5)	0.6 (.2–1.4)
Adjusted^b	1.0	1.6 (.6–4.3)	0.8 (.3–2.3)	0.8 (.3–2.1)
sCD14 (60 cases/120 controls)^a
Unadjusted	1.0	0.9 (.4–2.4)	3.0 (1.2–7.3)	1.9 (.8–4.8)
Adjusted^b	1.0	0.7 (.3–2.2)	2.8 (1.0–8.0)	1.8 (.6–5.4)
IL-6 (45 cases/99 controls)^a
Unadjusted	1.0	1.3 (.5–3.9)	1.8 (.6–5.0)	2.5 (.9–7.0)
Adjusted^b	1.0	0.8 (.2–2.9)	1.6 (.5–5.3)	2.0 (.6–6.3)
CRP (59 cases/120 controls)^a
Unadjusted	1.0	1.5 (.6–3.7)	1.2 (.5–3.1)	1.7 (.7–4.2)
Adjusted^b	1.0	1.3 (.5–3.7)	1.3 (.5–3.8)	1.6 (.6–4.4)

Abbreviations: CI, confidence interval; CRP, C-reactive protein; I-FABP, intestinal fatty acid binding protein; IL-6, interleukin 6; OR, odds ratio; sCD14, soluble CD14.

^aThe number of cases and controls with available data is shown for each biomarker.

^bOdds ratio for mortality between 6 weeks and 6 months of age based on quartiles of biomarkers measured in plasma at 6 weeks of age, adjusted for maternal parity and marital status, and infant sex, 6-week weight, and 6-week viral load in a logistic regression model.