Table 1.
Parameter | MXF | MXF + DAV132 | P Value |
---|---|---|---|
D1 | |||
AUC0-24h, µg/mL.h | 42.1 (17%) | 41.9 (23%) | .81 |
Cmax, µg/mL | 4.02 (33%) | 4.63 (21%) | .10 |
D5 | |||
AUC0-24h, µg/mL.h | 57.6 (24%) | 50.5 (22%) | .14 |
Cmax, µg/mL | 4.89 (25%) | 4.60 (27%) | .52 |
Geometric means (coefficient of variation %) are shown. Statistical comparison of groups was performed on log values.
Abbreviations: AUC0–24h, Area under the time curve between 0 and 24 h; Cmax, maximal concentration; MXF, moxifloxacin.