Table 1.

Setting-Specific Model Inputs for a Hypothetical Population, Using Generic Model Inputs Published Elsewhere

Model input	Value	Notes
No. of subpopulations	2	1 undervaccinated subpopulation and 1 general population
Initial age distribution
0–2 mo	0.01	Age groups of ≥5 y from a previously published hypothetical population [2] were split into groups of 5–15 y and ≥15 y, according to the age distribution in “less developed regions excluding China” [75], to accommodate the subsequently developed generically mixing age groups of 0–4, 5–14, and ≥15 y [33]
3–59 mo	0.15
5–14 y	0.25
≥15 y	0.59
Birth rate, births/person/y	0.02	Adopted from previously published hypothetical population [2]
Death rate, deaths/person/y	0.02	Adopted from previously published hypothetical population [2] and applied equally to each age group
Basic reproduction number	10	Adopted from previously published hypothetical population [2]
Proportion of transmission via oropharyngeal route	0.3	Adopted from previously published hypothetical population [2]
Average per-dose OPV take rate for serotype 1	0.5	Similar to typical values in low-income countries for bivalent OPV [33, 34]
Routine immunization coverage with exactly 3 OPV doses in the general population	0.95	Fixed well above the theoretical threshold of 0.92 implied by the other setting-specific inputs from this table

Generic model inputs are from reports by Duintjer Tebbens et al [33] and Thompson et al [34].

Abbreviation: OPV, oral poliovirus vaccine.