Table 2.
Demographic, Clinical Data, and Viral Loads According to the Most Frequent Respiratory Syncytial Virus Genotypes
| GA2 (n = 131) |
GA5
(n = 33) |
BA
(n = 69) |
P value | |
|---|---|---|---|---|
| Demographic characteristics | ||||
| Age, months | 2.1 [1.2–4.1] |
2.4 [0.8–5.7] |
2.2 [1.1–3.4] |
.85 |
| Gender, n (%) | ||||
| Male | 73 (56) | 20 (61) | 36 (52) | .71 |
| Female | 58 (42) | 13 (39) | 33 (48) | |
| Race/ethnicity, n (%) | ||||
| White | 97 (74) | 11 (33) | 40 (58) | |
| Black | 20 (15) | 6 (18) | 10 (15) | <.01 |
| Hispanic | 10 (8) | 15 (46) | 12 (17) | |
| Other | 4 (3) | 1 (3) | 7 (10) | |
| Breastfeeding (%) | 29 | 33 | 39 | .39 |
| Second hand smoking (%) | 42 | 21 | 29 | .06 |
| Daycare (%) | 20 | 14 | 9 | .44 |
| Siblings (%) | 79 | 93 | 86 | .08 |
| Disease severity | ||||
| Days of symptoms | 4 [3–6] | 4 [2–5] | 5 [3–7] | .04 |
| O2 requirement | ||||
| n (%) | 100 (76) | 19 (61)a | 47 (68) | .17 |
| Duration of oxygen (days) | 1.5 [0.1–4] | 1 [0–2]) | 1 [0–3] | .10 |
| PICU, n (%) | 31 (24) | 4 (12) | 15 (22) | .35 |
| CDSS | 5 [3–8] | 5 [3–7] | 5 [3–8] | .70 |
| LOS, days | 3 [2–5] | 3 [2–8.5] | 3 [2–6] | .49 |
| Viral load, log10 copies/mL | 5.86 [5.03–6.45] |
6.59 [6.10–6.94] |
5.23 [4.32–6.13] |
<.01 |
Continuous variables were analyzed using the Kruskall–Wallis tests and categorical variables using Fisher’s exact or Chi-square test. Data are reported as medians, 25%–75% interquartile range.
Abbreviations: PICU, pediatric intensive care unit; CDSS, clinical disease severity score; LOS, length of stay.
aFor GA5 genotype O2 administration was not documented in two patients.
Bold highlights the significant.