Elderly individuals (n = 187) with congestive heart failure (CHF) are likely to have a poor varicella-zoster virus (VZV) vaccine response. The odds of achieving a ≥2-fold VZV vaccine response was determined by multiple logistic regression, with adjustments for age, sex, and log2 baseline VZV response, for the following diseases: CHF, peripheral vascular disease (PVD), dementia (DEM), chronic pulmonary disease (CPD), diabetes mellitus (DM), and hemiplegia (HEM). Odds ratios (ORs) and P values are listed at right.