Figure 3.

Antibody levels dramatically decline with viral load suppression after antiretroviral treatment (ART) initiation. During total viral suppression, antibody levels dramatically decline in both early and late-treated groups. Since antibody concentrations were higher in the late-treated group, the slope of the decline is much steeper. While concentrations in the early treated group seem to reach a new steady state or increase, those in the late-treated group continue to decline. Colors correspond to the same study participant throughout the antibody measurements. Abbreviations: AM-Vitros, avidity-modified Vitros assay; LAg, Sedia limiting antigen; LS-Vitros, less sensitive Vitros assay; ODn, normalized OD; S/Co, signal-to-cutoff ratio.