Figure 3.
Cross-sectional seroprevalence in the US population. A, Age-stratified, cross-sectional number of detectable serotypes among US females (mean and 95% confidence interval). There was a significant decrease in mean number of serotypes between the age groups of 30–39 and 40–49 years (*P < .05), and the age groups of 40–49 and 50–59 years (**P < .01), respectively. B, The cross-sectional measure from (A) is stratified by cumulative sexual exposure as measured by self-reported number of lifetime sex partners (LTSPs) up to 50 total partners. For the strata “LTSP = 5–6” and “LTSP = 10–19,” there was a significant decrease in mean number of serotypes between the age groups of 30–39 and 40–49 years (P < .01 and P < .05, respectively), but no difference between the age groups of 40–49 and 50–59 years. In the remaining LTSP strata, no decrease in mean number of serotypes was observed after age 30–39 years.